High expression of TAZ indicates a poor prognosis in retinoblastoma

Diagnostic Pathology

Table 4 Cox univariate analysis of overall survival

Variables	SE value	Hazard ratio	Risk ratio (95 % CI)	P value
Age (≥5 y)	1.043	0.835	0.108–6.451	0.863
Gender (female)	0.558	0.806	0.270–2.409	0.700
Tumor enucleated location (left)	0.536	0.702	0.246–2.006	0.702
Primary tumor (cT3 + T4)	0.680	0.122	0.032–0.462	0.002*
Regional lymph node (cN1 + N2)	0.793	0.135	0.028–0.638	0.012*
cTNM stage (III + IV)	1.043	0.098	0.013–0.760	0.026*
Largest tumor base (>15 mm)	0.591	0.297	0.093–0.948	0.040*
Tumor thickness (>10 mm)	0.545	0.668	0.230–1.943	0.459
Differentiation (poorly)	0.789	0.085	0.018–0.401	0.002*
TAZ high expression	0.601	0.314	0.112–1.129	0.042*

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