Table 1 Association between the clinicopathological parameters and expression of miRNAs in the osteosarcoma patients
Clinicopathological features | No. of cases | Expression of miR-130b | Expression of miR-218 | P value of miR-130b | P value of miR-218 | ||
|---|---|---|---|---|---|---|---|
Low = 11 | High = 19 | Low = 17 | High = 13 | ||||
Gender | 0.741 | 0.712 | |||||
Male | 17 | 7 | 10 | 11 | 6 | ||
Female | 13 | 4 | 9 | 6 | 7 | ||
Age | 0.517 | 0.483 | |||||
<24 | 12 | 4 | 8 | 7 | 5 | ||
≥25 | 18 | 7 | 11 | 10 | 8 | ||
Tumor diameter (cm) | 0.013 | 0.019 | |||||
≤6 | 16 | 9 | 7 | 6 | 10 | ||
>6 | 14 | 2 | 12 | 11 | 3 | ||
Histology | 0.51 | 0.503 | |||||
Conventional osteosarcoma | 20 | 6 | 14 | 11 | 9 | ||
Others | 10 | 5 | 5 | 6 | 4 | ||
Clinical stage | 0.009 | 0.007 | |||||
I | 12 | 8 | 4 | 4 | 8 | ||
II | 10 | 3 | 7 | 6 | 4 | ||
III | 8 | 0 | 8 | 7 | 1 | ||
Distant metastasis | <0.001 | <0.001 | |||||
No | 18 | 8 | 10 | 7 | 11 | ||
Yes | 12 | 3 | 9 | 10 | 2 | ||