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Table 1 Association of FAM3C expression with clinicopathological features in ESCC

From: Prognostic significance of FAM3C in esophageal squamous cell carcinoma

Clinical features Cases FAM3C mRNA expression P value
low level (%) high level (%)
Age (years old)     0.204
 ≤59 49 28 (57.1 %) 21 (42.9 %)  
 >59 58 26 (44.8 %) 32 (55.2 %)  
Gender     0.954
 Male 79 40 (50.6 %) 39 (49.4 %)  
 Female 28 14 (50.0 %) 14 (50.0 %)  
Location     0.811
 Upper 12 5 (41.7 %) 7 (58.3 %)  
 Middle 60 31 (51.7 %) 29 (48.3 %)  
 Lower 35 18 (51.4 %) 17 (48.6 %)  
Differentiation     0.843
 Grade 1 20 9 (45.0 %) 11 (55.0 %)  
 Grade 2 57 29 (50.9 %) 28 (49.1 %)  
 Grade 3 30 16 (53.3 %) 14 (46.7 %)  
pT stage     0.014
 T1-2 25 18 (72.0 %) 7 (28.0 %)  
 T3-4 82 36 (43.9 %) 46 (56.1 %)  
pN stage     0.026
 N0 56 34 (60.7 %) 22 (39.3 %)  
 N1-3 51 20 (39.2 %) 31 (60.8 %)  
TNM stage     0.003
 I-II 60 38 (63.3 %) 22 (36.7 %)  
 III 47 16 (34.0 %) 31 (66.0 %)  
  1. Statistical significance (P < 0.05) is shown in bold