Table 1 Association of FAM3C expression with clinicopathological features in ESCC
From: Prognostic significance of FAM3C in esophageal squamous cell carcinoma
| Clinical features | Cases | FAM3C mRNA expression | P value | |
|---|---|---|---|---|
| low level (%) | high level (%) | |||
| Age (years old) | 0.204 | |||
| ≤59 | 49 | 28 (57.1 %) | 21 (42.9 %) | |
| >59 | 58 | 26 (44.8 %) | 32 (55.2 %) | |
| Gender | 0.954 | |||
| Male | 79 | 40 (50.6 %) | 39 (49.4 %) | |
| Female | 28 | 14 (50.0 %) | 14 (50.0 %) | |
| Location | 0.811 | |||
| Upper | 12 | 5 (41.7 %) | 7 (58.3 %) | |
| Middle | 60 | 31 (51.7 %) | 29 (48.3 %) | |
| Lower | 35 | 18 (51.4 %) | 17 (48.6 %) | |
| Differentiation | 0.843 | |||
| Grade 1 | 20 | 9 (45.0 %) | 11 (55.0 %) | |
| Grade 2 | 57 | 29 (50.9 %) | 28 (49.1 %) | |
| Grade 3 | 30 | 16 (53.3 %) | 14 (46.7 %) | |
| pT stage | 0.014 | |||
| T1-2 | 25 | 18 (72.0 %) | 7 (28.0 %) | |
| T3-4 | 82 | 36 (43.9 %) | 46 (56.1 %) | |
| pN stage | 0.026 | |||
| N0 | 56 | 34 (60.7 %) | 22 (39.3 %) | |
| N1-3 | 51 | 20 (39.2 %) | 31 (60.8 %) | |
| TNM stage | 0.003 | |||
| I-II | 60 | 38 (63.3 %) | 22 (36.7 %) | |
| III | 47 | 16 (34.0 %) | 31 (66.0 %) | |