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Table 5 Diagnostic value of tests in discrimination of malignant from benign thyroid lesions

From: Defining the value of CD56, CK19, Galectin 3 and HBME-1 in diagnosis of follicular cell derived lesions of thyroid with systematic review of literature

For malignancy

HBME-1

Galectin-3

CK19

CD56

Sensitivity

71.31 %

88.52 %

75.41 %

58.20 %

Specificity

84.81 %

64.56 %

70.89 %

92.41 %

Positive Likelihood Ratio

4.69

2.5

2.59

7.66

Negative Likelihood Ratio

0.34

0.18

0.35

0.45

Disease prevalence

60.70 %

60.70 %

60.70 %

60.70 %

Positive Predictive Value

87.88 %

79.41 %

80.00 %

92.21 %

Negative Predictive Value

65.69 %

78.46 %

65.12 %

58.87 %

Odds ratio

13.8786

14.051

7.4667

16.9379