Table 3 Proposed three parameters scoring system
Parameter | Score 0 | Score 1 | Score 2 | Score 3 | Score 4 | Total scores |
|---|---|---|---|---|---|---|
Ki-67 | <2 % | 2–5 % | 6–10 % | 11–20 % | >20 % | p16-Ki-67 score: 0–7 p16-Ki-67-HMB45 score: 0–9 |
p16 | >50 % | 11–50 % | 1–10 % | 0 % | - | |
HMB45 | Gradient present | Gradient doubtful or inconclusive | Gradient absent | - | - |