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Table 3 Proposed three parameters scoring system

From: A p16-Ki-67-HMB45 immunohistochemistry scoring system as an ancillary diagnostic tool in the diagnosis of melanoma

Parameter Score 0 Score 1 Score 2 Score 3 Score 4 Total scores
Ki-67 <2 % 2–5 % 6–10 % 11–20 % >20 % p16-Ki-67 score: 0–7
p16-Ki-67-HMB45 score: 0–9
p16 >50 % 11–50 % 1–10 % 0 % -
HMB45 Gradient present Gradient doubtful or inconclusive Gradient absent - -