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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Clinical utility of TERT promoter mutations and ALK rearrangement in thyroid cancer patients with a high prevalence of the BRAF V600E mutation

Fig. 1

Structure of the wild-type TERT gene and representative sequencing electropherograms of the genomic DNA of the TERT promoter. The g.1295228 C > T (C228T) and g.1295250 C > T (C250T) mutations within the TERT promoter gene result in a cytosine-to thymine transition at 124 bp (c.-124C > T) and 146 bp (c.-146C > T) upstream of the ATG start codon, respectively. g.1295228 C > A (C228A) is a cytosine-to adenine transition at the 1 295 228 position of chr5

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