Abnormal villous morphology mimicking a hydatidiform mole associated with paternal trisomy of chromosomes 3,7,8 and unipaternal disomy of chromosome 11

Table 1 Genotypes of parental and villous tissue for loci amplified by the AmpFlSTR kit

Locus	chr	Patient	Villi	Partner	Ploidy	Parental contributions
D8S1179	8	10 - 12	12 < 14	11 - 14	3n	M,P2,P2
D21S11	21	28 - 30	28	28 - 30	NI	NI
D7S820	7	9 - 11	8 - 9 - 12	8 - 12	3n	M,P1,P2
CSF1PO	5	10 - 11	10 - 12	11 - 12	2n	M,P
D3S1358	3	15 - 18	15 > 18	15 - 16	3n	NI
THO1	11	6 - 9.3	8	7 - 8	NI	P
D13S317	13	11 - 12	11 - 12	11	2n	NI
D16S539	16	13	11 - 13	11	2n	M,P
D2S1338	2	19 - 23	19 - 23	23 - 24	2n	NI
D19S433	19	14 - 15	14	14 - 15	NI	NI
vWA	12	17 - 18	16 - 18	16	2n	M,P
TPOX	2	8 - 11	8 - 11	8	2n	NI
D18S51	18	13 - 14	13 - 19	13 - 17	2n	M,P
AMEL		X	X	XY	NI	NI
D5S818	5	12 - 14	11 - 14	11	2n	M,P
FGA	4	21 - 28	21 - 22	22 - 24	2n	M,P

Alleles are numbered by comparison with the allelic ladder provided. chr, chromosome; M, maternal allele; P, paternal allele; P1, and P2, smaller and larger paternal allele respectively; NI, not informative

ISSN: 1746-1596