Table 1 Case Summary and Comparison of 8 Mammary Myofibrosarcomas in the Worldwide Literature (1997-2015)
From: Low-grade myofibroblastic sarcoma arising in fibroadenoma of the breast-A case report–
Case No. | Clinical Findings | Pathologic Findings | Immunohistochemical Findings | Therapy and F/U data |
|---|---|---|---|---|
Sex/age(Pre.y) | Site, Size, DUR | Grade, Necrosis, Mitosis | Positive/Negative | |
1. F/55(1997) | UOQ, 2- > 8 cm, 1 W | High Gr, +, 10–45/10HPFs | VM,SMA,FN;+/DSM,LMN,COLIV;− | Mastectomy with LA. Died 11 M with meta. |
2. M/60(1999) | UOQ, 2.5 cm, 1 M | Low Gr, +, 10/10HPFs | VM,SMA;+/DSM,LMN,S100,CD34;− | Mastectomy with LA. Alive 10Y with recurrence |
3. F/59(1999) | NC, 2.3 cm, NC | Low Gr, -, 6–15/10HPFs | VM,SMA,FN;+/DSM,LMN,S100,CD34;− | Mastectomy with LRT. NED 20 M |
4. F/72(2001) | NC, 3.4 cm, NC | Low Gr, +, 2/10HPFs | SMA,MSA,DSM:+/Cytokeratin:− | Mastectomy. Died 12 M with meta. |
5. F/51(2003) | 4Qs, 22 cm, 3 M | High Gr, + 8–35/10HPFs | VM,SMA;+/S100,DSM,h-CAL,PCK;− | Mastectomy with CRT. Alive 24 M |
6. F/46(2005) | UOQ, 2 cm, 6 M | Low Gr, -, NC | VM,SMA,FN;+/PCK,COLIV;− | Mastectomy. NED 12 M |
7. F/81(2011) | NC, 4.2 cm, 2 W | Low Gr, NC, many/10HPFs | VM,SMA,bcl-2;+/DSM,S100,c-kit,CD34;− | Mastectomy with RT. Alive 16 M with meta. |
8a. F/61(2015) | UOQ, 3–> 5 cm, 8 M | Low Gr, +, 5–16/10HPFs | VM,SMA,FN,calponin;+/DSM,CD34,p63,bcl-2;− | Lumpectomy. NED 18 M |