Fig. 4From: Epithelioid inflammatory myofibroblastic sarcoma: a clinicopathological, immunohistochemical and molecular cytogenetic analysis of five additional cases and review of the literatureImmunohistochemical and genetic features of EIMS. a Immunohistochemistry for ALK showed a nuclear membrane staining pattern (400 × original magnification). b Case 3 showed ALK cytoplasmic staining with perinuclear accentuation (200 × original magnification). c Diffuse and strong positivity for desmin (200 × original magnification). d Fluorescence in situ hybridization (FISH) showed split apart of the red and green signals, confirming the presence of ALK rearrangement (1000 × original magnification)Back to article page