Fig. 2

The results of HER2 gene amplification status evaluated by FISH assay. A-1 was section of cell lines sample without HER2 gene amplification (MCF-7) while A-2 was that with positive HER2 gene amplification (SKBR-3). B-1 was section of agarose gel within cell lines sample without HER2 gene amplification (MCF-7) while A-2 was that with positive HER2 gene amplification (SKBR-3). C-1 was section of xenograft tumor sample without HER2 gene amplification (MCF-7) while A-2 was that with positive HER2 gene amplification (SKBR-3). D-1 was section of clinical specimen without HER2 gene amplification (A2) while A-2 was that with positive HER2 gene amplification (A12). The magnification was 1000 power