Table 4 Association of MUC1 expression levels and subcellular localization patterns with clinicopathological profile
| Â | MUC1 subcellular localization | MUC1 expression level | ||||
|---|---|---|---|---|---|---|
|  | LC (n = 15) | CM (n = 7) |  | Low (n = 11) | High (n = 11) |  |
Age (years) | ||||||
  > 61 | 7 | 4 | 0.65 | 5 | 6 | 0.66 |
  < 60 | 8 | 3 |  | 6 | 5 |  |
Histological type | ||||||
 IDC | 5 | 4 | 0.28 | 7 | 2 | 0.09 |
 ILC | 6 | 3 |  | 3 | 6 |  |
 MC | 4 | 0 |  | 1 | 3 |  |
SRC (%) | ||||||
  > 31 | 8 | 4 | 0.87 | 5 | 7 | 0.39 |
  < 30 | 7 | 3 |  | 6 | 4 |  |
SRC type | ||||||
 Non-ICL | 10 | 4 | 0.67 | 8 | 6 | 0.38 |
 ICL | 5 | 3 |  | 3 | 5 |  |
Tumor size (cm) | ||||||
  > 2.1 | 6 | 6 | 0.04 | 9 | 3 | 0.01 |
  < 2.0 | 9 | 1 |  | 2 | 8 |  |
Nuclear grade | ||||||
 1 | 11 | 3 | 0.28 | 3 | 11 | 0.002 |
 2 | 3 | 2 |  | 5 | 0 |  |
 3 | 1 | 2 |  | 3 | 0 |  |
LN status | ||||||
 Positive | 2 | 6 | 0.001 | 7 | 1 | 0.008 |
 Negative | 13 | 1 |  | 4 | 10 |  |
LVI | ||||||
 Positive | 2 | 5 | 0.006 | 5 | 2 | 0.17 |
 Negative | 13 | 2 |  | 6 | 9 |  |
ER | ||||||
 Positive | 11 | 4 | 0.45 | 5 | 10 | 0.02 |
 Negative | 4 | 3 |  | 6 | 1 |  |
TN vs other types | ||||||
 TN | 3 | 3 | 0.26 | 5 | 1 | 0.055 |
 Other types | 12 | 4 |  | 6 | 10 |  |
Ki67 (%) | ||||||
  > 20 | 2 | 4 | 0.03 | 5 | 1 | 0.055 |
  < 19 | 13 | 3 |  | 6 | 10 |  |
Recurrence | ||||||
 Positive | 0 | 2 | 0.03 | 2 | 0 | 0.14 |
 Negative | 15 | 5 |  | 9 | 11 |  |