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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Individual and co-expression patterns of nerve growth factor and heme oxygenase-1 predict shorter survival of gastric carcinoma patients

Fig. 1

The expression of NGF and HO1 in human gastric cancer cells and human gastric carcinoma tissue. a Validation of the anti-NGF and anti-HO1 antibodies used in this study. The expressions of NGF and HO1 were seen in western blotting analysis in four gastric cancer cell lines (MKN28, MKN45, KATO-III, and NCI-N8). b Immunohistochemical expression of NGF and HO1 in normal gastric mucosa and gastric carcinoma. Original magnification: low-power images; ×20, high-power images; ×400. c Immunohistochemical staining scores of NGF and HO1 in normal gastric mucosa and gastric carcinoma. *; p < 0.05, **; p < 0.001. d Statistical analysis for the determination of immunohistochemical positivity for NGF (arrow) and HO1 (arrow head). The cut-off points were determined by receiver operating characteristic curve analysis at the highest area under the curve value for the estimation overall survival of gastric carcinoma patients

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Diagnostic Pathology

ISSN: 1746-1596

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