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Fig. 5 | Diagnostic Pathology

Fig. 5

From: Data integration from pathology slides for quantitative imaging of multiple cell types within the tumor immune cell infiltrate

Fig. 5

Error in immune cell counts caused by tumor mask transfer. Bland-Altman plots illustrating errors of immune cell subtypes inside and outside the tumor mask. (a-c) The difference of CD68+, CD8+ or CD4+ counts between transferred and ground truth tumor masks is plotted on the y-axis. The x-axis represents the mean cell count underneath transferred and manual masks. The red line indicates the mean error and blue lines the 95% confidence interval of the error. p-values were calculated by a one-sided t-test. Zero indicates perfect concordance in cell counts underneath both masks. (d-f) Same as (a-c) but for TIL numbers outside the tumor area. (g) Representative image of transferred versus ground truth tumor mask

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