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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Composite intestinal adenoma-microcarcinoid in the colon and rectum: a case series and historical review

Fig. 3

Histological and immunohistochemical features of composite intestinal adenoma-microcarcinoid, mimicking adenoma with squamous metaplasia (squamous morules). a Low power magnification shows adenomatous glands with a few eosinophilic cell nests (black arrows) in basal lamina propria (×40). b High power magnification shows adenomatous glands and eosinophilic cell nests resembling squamous metaplasia (×200). c Immunohistochemical staining for synaptophysin shows diffuse cytoplasmic reactivity in the eosinophilic cells nests, supporting the neuroendocrine differentiation (×200). d The neuroendocrine component is negative for chromogranin-A on immunostaining (×200)

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Diagnostic Pathology

ISSN: 1746-1596

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