Fig. 3From: p53 aberrations in low grade endometrioid carcinoma of the endometrium with nodal metastases: possible insights on pathogenesis discerned from immunohistochemistryMorphologic and immunophenotypic features of the p53-aberrant areas of tumor at its primary site (arrows indicate focus of squamous differentiation, consistent with an endometrioid histotype). a, b Morphologic features, showing increased atypia and mitotic activity in a p53-aberrant area of the tumor, compared to the p53-wild type areas as illustrated in Fig. 1b [H and E, original magnification: 40 x]. c p53-aberrant immunophenotype. [original magnifications: ×40]. d, 1H: p16-diffusely positive immunophenotype. [original magnifications: ×40]Back to article page