Fig. 3
From: Novel splice site IDUA gene mutation in Tunisian pedigrees with hurler syndrome
Effects of IDUA splice site mutation. a Mutation c.1650 + 1G > T, which abolies a splice donor (GT) within intron 11, resulting in skipping of the exon 11. b Mutation c.1650 + 1G > T, which creates an alternate cryptic splicing site, resulting in the deletion of 169 nucleotides at the end of the exon 11 giving a new size of exon 11 about 135 bp. c Mutation c.1650 + 1G > T which retains the part of the intron 11