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Table 2 Data findings: CVs and percentage variation of wild type and mutant sequences in intron 11 of IDUA gene (http://www.umd.be/HSF/)

From: Novel splice site IDUA gene mutation in Tunisian pedigrees with hurler syndrome

Splice site type Motif New splice site Wild type (WT) CV (0–100) Mutant CV (0–100) If cryptic site use, exon length variation (bp) Variation (%)
Acceptor CCGCCCGGGCAGgc ccgcccgggcagTC 84.05 79.76 NA −5.1
Acceptor CGGGCAGgcaagtg ccgggcagtcaagTG 64.94 68.57 NA New site + 5.59
Donor CAGgcaagt CAGtcaagt 100 80.03 135 WT site broken −19.97
Acceptor Ggcaagtggcagtc gtcaagtggcagTC 73.99 77.65 NA + 4.95