Evaluation of the correlation of MACC1, CD44, Twist1, and KiSS-1 in the metastasis and prognosis for colon carcinoma

Table 2 The correlation between MACC1, or CD44, or Twist1, or KiSS-1 and clinicopathological characteristics in colon adenocarcinoma

Variable	MACC1		P	CD44		P	Twist1		P	KiSS-1		P
Variable	Negative	Positive	P	Negative	Positive	P	Negative Positive		P	Negative	Positive	P
Gender			0.239			0.929			0.783			0.564
Male	51	91		64	78		50	92		87	55
Female	31	39		32	38		26	44		40	30
Age (years)			0.263			0.927			0.775			0.833
≤60	48	86		61	73		49	85		81	53
> 60	34	44		35	43		27	51		46	32
Size (cm)			0.081			0.375			0.085			< 0.001
≤2.0	10	23		14	19		10	23		16	17
> 2.0, ≤5.0	38	72		46	64		34	76		80	30
> 5.0	34	35		36	33		32	37		31	38
Location			0.863			0.156			0.507			0.526
Ascending	17	25		21	21		13	29		21	21
Transverse	22	42		25	39		22	42		39	25
Descending	13	20		11	22		10	23		21	12
Sigmoid	30	43		39	34		31	42		46	27
Gross type			0.056			0.406			0.002			0.929
Ulcerative	27	38		35	30		31	34		37	28
Infiltrating	10	36		20	26		6	40		28	17
Polypoid	29	39		28	40		25	43		41	27
Colloid	16	17		13	20		14	19		21	12
Invasion			0.035			0.040			0.002			0.003
Submucosa	20	16		21	15		19	17		13	23
Muscularis	19	45		29	35		30	34		38	26
Subserosa	41	60		45	56		25	76		66	35
Visceral peritoneum	2	9		1	10		2	9		10	1
Grade			0.032			0.024			< 0.001			0.745
Well	18	14		20	12		19	13		18	14
Moderate	52	83		62	73		53	82		80	55
Poor	12	33		14	31		4	41		29	16
LNM stages			< 0.001			< 0.001			< 0.001			< 0.001
N0	71	65		85	51		64	72		60	76
N1	11	59		11	59		12	58		61	9
N2	0	6		0	6		0	6		6	0
TNM stage			< 0.001			< 0.001			< 0.001			< 0.001
I	37	32		47	22		40	29		23	46
II	34	33		38	29		24	43		37	30
III	11	65		11	65		12	64		67	9

ISSN: 1746-1596