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Table 2 Binding affinity of mAbs 1B1 and 4C2

From: Development and characterization of an HPV18 detection kit using two novel HPV18 type-specific monoclonal antibodies

mAb

HPV18

Othersb

Ka (Ms− 1)a

Kd (s− 1)a

KD (M)a

Ka (Ms− 1)

Kd (s− 1)

KD (M)

1B1

9.31 × 105

1.92 × 10− 3

2.06 × 10−9

N/Ac

N/A

N/A

4C2

2.38 × 106

1.78 × 10−2

7.45 × 10− 9

N/A

N/A

N/A

  1. aKa is the binding constants, Kd is the dissociation constant, KD is the binding affinity;
  2. bHPV L1-VLP of other types, including HPV16, HPV58, HPV6, HPV11, HPV31VLP, HPV33, HPV45, and HPV52;
  3. cNot Applicable
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Diagnostic Pathology

ISSN: 1746-1596

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