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Table 3 Summary of clinicopathologic prognostic factors according to the PD-L1 status

From: Prognostic significance of the programmed death ligand 1 expression in clear cell renal cell carcinoma and correlation with the tumor microenvironment and hypoxia-inducible factor expression

   PD-L1 Staining Test Statistics (χ2; P)
Negative n (%) Positive n (%)
Renal Pelvis Invasion No 115 (92.0) 18 (90.0) 0.091; 0.763
Yes 10 (8.0) 2 (10.0)
Adrenal gland direct Invasion No 123 (98.4) 20 (100) 0.324; 0.569
Yes 2 (1.6) 0 (0)
Adrenal Gland Metastasis No 123 (98.4) 19 (95) 0.754; 0.384
Yes 2 (1.6) 1 (5)
Sarcomatoid Component No 119 (95.2) 18 (90) 0.894; 0.344
Yes 6 (4.8) 2 (10)
Necrosis No 80 (64.0) 13 (65) 0.007; 0.931
Yes 45 (36.0) 7 (35)
Lymphovascular Invasion No 109 (87.2) 16 (80) 0.752; 0.386
Yes 16 (12.8) 4 (20)
Ureter Invasion No 123 (98.4) 20 (100) 0.324; 0.569
Yes 2 (1.6) 0 (0)
Renal Vein Invasion No 117 (93.6) 18 (90) 0.348; 0.555
Yes 8 (6.4) 2 (10)
Distant Metastasis No 100 (80.0) 15 (75) 0.263; 0.608
Yes 25 (20.0) 5 (25)
Lymph Node Metastasis No 117 (93.6) 19 (95.0) 0.058; 0.810
Yes 8 (6.5) 1 (5.0)
WHO/ISUP grade 1–2 68 (54.4) 6 (30) 4.108; 0.043
3–4 57 (45.6) 14 (70)