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Table 3 Summary of clinicopathologic prognostic factors according to the PD-L1 status

From: Prognostic significance of the programmed death ligand 1 expression in clear cell renal cell carcinoma and correlation with the tumor microenvironment and hypoxia-inducible factor expression

  

PD-L1 Staining

Test Statistics (χ2; P)

Negative n (%)

Positive n (%)

Renal Pelvis Invasion

No

115 (92.0)

18 (90.0)

0.091; 0.763

Yes

10 (8.0)

2 (10.0)

Adrenal gland direct Invasion

No

123 (98.4)

20 (100)

0.324; 0.569

Yes

2 (1.6)

0 (0)

Adrenal Gland Metastasis

No

123 (98.4)

19 (95)

0.754; 0.384

Yes

2 (1.6)

1 (5)

Sarcomatoid Component

No

119 (95.2)

18 (90)

0.894; 0.344

Yes

6 (4.8)

2 (10)

Necrosis

No

80 (64.0)

13 (65)

0.007; 0.931

Yes

45 (36.0)

7 (35)

Lymphovascular Invasion

No

109 (87.2)

16 (80)

0.752; 0.386

Yes

16 (12.8)

4 (20)

Ureter Invasion

No

123 (98.4)

20 (100)

0.324; 0.569

Yes

2 (1.6)

0 (0)

Renal Vein Invasion

No

117 (93.6)

18 (90)

0.348; 0.555

Yes

8 (6.4)

2 (10)

Distant Metastasis

No

100 (80.0)

15 (75)

0.263; 0.608

Yes

25 (20.0)

5 (25)

Lymph Node Metastasis

No

117 (93.6)

19 (95.0)

0.058; 0.810

Yes

8 (6.5)

1 (5.0)

WHO/ISUP grade

1–2

68 (54.4)

6 (30)

4.108; 0.043

3–4

57 (45.6)

14 (70)