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Table 1 Correlations between TILs and clinicopathologic characteristics in TNBCs

From: Predictive value of tumor-infiltrating lymphocytes to pathological complete response in neoadjuvant treated triple-negative breast cancers

Characteristics No. of patients (%) P-value of sTILs P-value of iTILs
Age (years)
  < 50 80 (48.2) 0.87a 0.79a
  ≥ 50 86 (51.8)   
Tumor size (cm)
  ≤ 2 22 (13.2) 0.88b 0.16b
 2–5 115 (69.3)   
  > 5 29 (17.5)   
Lymph node status
 Negative 53 (31.9) 0.78a 0.23a
 Positive 113 (68.1)   
Histological type
 IDC 164 (98.8) 0.58a 0.33a
 Special type 2 (1.2)   
Histological grade
 2 31 (18.7) 0.004a+ 0.03a+
 3 135 (81.3)   
LVI
 Negative 130 (78.3) 0.17a 0.03a+
 Positive 36 (21.7)   
Miller-Payne grade
 1 17 (10.2) 0.001b+ 0.06b
 2 26 (15.7)   
 3 32 (19.3)   
 4 24 (14.4)   
 5 67 (40.4)   
NAC
 Anthracycline + paclitaxel 136 (81.9) 0.98a 0.99a
 Paclitaxel + platinum 30 (18.1)   
  1. Abbreviations: TNBCs triple-negative breast cancers, sTILs stromal tumor-infiltrating lymphocytes, iTILs intratumoral tumor-infiltrating lymphocytes, IDC invasive ductal carcinoma of no special type, LVI lymphovascular invasion, NAC neoadjuvant chemotherapy
  2. aMann-Whitney test
  3. bKruskal-Wallis test
  4. +The p value is significant