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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Pleomorphic lobular carcinoma of the breast with osteoclast-like giant cells: a case report and review of the literature

Fig. 3

Deleterious mutation in CDH1 found in the case studied. a Lollipop representation of deleterious mutation c.866delC in CDH1. E-cadherin motifs are represented in different colours. b IGV-browser view of mutation c.del866C through massive sequencing data from the case studied. Mutation is represented in both DNA strands (5′- > 3′, red, and 3′- > 5′, blue) in a high frequency of reads, supporting a homozygous status (through LOH) within tumour cells

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