Table 2 Correlation between cytoplasmic REDD1 expression and clinicopathologic factors
Characteristic | REDD1 expression | Total No. | χ2 | P-value | |
|---|---|---|---|---|---|
Low expression No. (%) | High expression No. (%) | ||||
Age | |||||
20- | 4(66.7) | 2(33.3) | 6 | 0.911* | |
30- | 7(70.0) | 3(30.0) | 10 | ||
40- | 31(67.4) | 15(32.6) | 46 | ||
50- | 42(68.9) | 19(31.1) | 61 | ||
60- | 45(58.4) | 32(41.6) | 77 | ||
70- | 16(64.0) | 9(36.0) | 25 | ||
80- | 3(75.0) | 1(25.0) | 4 | ||
Stage | 20.283 | < 0.001 | |||
Stage I | 27(81.8) | 6(18.2) | 33 | ||
Stage II | 24(85.7) | 4(14.3) | 28 | ||
Stage III | 85(62.5) | 51(37.5) | 136 | ||
Stage IV | 12(37.5) | 20(62.5) | 32 | ||
Histologic type | < 0.001* | ||||
Serous carcinoma | 58(46.4) | 67(53.6) | 125 | ||
Mucinous carcinoma | 6(100.0) | 0(0.0) | 6 | ||
Endometrioid carcinoma | 30(96.8) | 1(3.2) | 31 | ||
Clear-cell carcinoma | 11(78.6) | 3(21.4) | 14 | ||
Mixed-type carcinoma | 43(81.1) | 10(18.9) | 53 | ||
Ascites | 18.699 | < 0.001 | |||
Yes | 75(54.7) | 62(45.3) | 137 | ||
No | 44(72.1) | 17(27.9) | 61 | ||
Unknown | 26(93.5) | 2(6.5) | 31 | ||
Chemotherapy response | < 0.001* | ||||
Responders | 119(74.8) | 40(25.2) | 159 | ||
Partial responders | 14(34.1) | 27(65.9) | 41 | ||
Non responders | 8(42.1) | 11(57.9) | 19 | ||
NC/URa | 7(70.0) | 3(30.0) | 10 | ||
CA125 | |||||
< 500 | 38(59.4) | 26(40.6) | 64 | 0.529* | |
≥ 500 | 38(58.5) | 27(41.5) | 65 | ||
Unknown | 72(72.0) | 28(28.0) | 100 | ||