Skip to main content

Table 1 Clinicopathological features of 150 patients with follicular thyroid tumors

From: Mutation profiles of follicular thyroid tumors by targeted sequencing

  FTC, n (%) FTA, n (%) FT-UMP, n (%) WDT-UMP, n(%)
Cases 53 48 32 17
Sex
 Male 16 (30) 16 (33) 12 (37) 5 (29)
 Female 37 (70) 32 (67) 20 (63) 12 (71)
Age at diagnosis
 Mean year 46 45 46 44
 Median (Quartiles) 50 (31–61) 47 (34–54) 44 (37–58) 43 (33–55)
Tumor size, cm
 Mean size 3.1 2.5 3.4 1.9
 Median (Quartiles) 2.5 (1.5–4.0) 2.5 (1.8–3.0) 2.5 (1.4–5.4) 1.2 (1.0–2.7)
Variant type
 Hürthle cell tumor 14 (26) 12 (25) 6 (19) 2 (18)
 Non-Hürthle cell tumor 39 (74) 36 (75) 26 (81) 14 (82)
Histologic type a
 Minimally invasive 25 (47)    
 Encapsulated angioinvasive 15 (28)    
 Widely invasive 13 (25)    
Lymph node metastasis
 Present 5 (9)
Distant metastasis
 Present 2 (4)
AJCC stage
 I~II 51 (96)
 III~IV 2 (4)
Follow-up time
 Median (Quartiles) 56 (46–65) 55 (42–65) 55 (47–60) 55 (29–74)
Disease Persistence/Recurrence
 Yes 8 (15) 0 (0) 0 (0) 0 (0)
 No 45 (85) 48 (100) 32 (100) 16 (100)
  1. a, based on the 2017 World Health Organization classification of endocrine tumors; Abbreviations: FTC follicular thyroid carcinoma, FTA follicular thyroid adenoma, FT-UMP follicular tumor of uncertain malignant potential, WDT-UMP well-differentiated tumor of uncertain malignant potential, AJCC American Joint Committee on Cancer, 8th edition staging;