Skip to main content

Table 1 Clinicopathological features of 150 patients with follicular thyroid tumors

From: Mutation profiles of follicular thyroid tumors by targeted sequencing

 

FTC, n (%)

FTA, n (%)

FT-UMP, n (%)

WDT-UMP, n(%)

Cases

53

48

32

17

Sex

 Male

16 (30)

16 (33)

12 (37)

5 (29)

 Female

37 (70)

32 (67)

20 (63)

12 (71)

Age at diagnosis

 Mean year

46

45

46

44

 Median (Quartiles)

50 (31–61)

47 (34–54)

44 (37–58)

43 (33–55)

Tumor size, cm

 Mean size

3.1

2.5

3.4

1.9

 Median (Quartiles)

2.5 (1.5–4.0)

2.5 (1.8–3.0)

2.5 (1.4–5.4)

1.2 (1.0–2.7)

Variant type

 Hürthle cell tumor

14 (26)

12 (25)

6 (19)

2 (18)

 Non-Hürthle cell tumor

39 (74)

36 (75)

26 (81)

14 (82)

Histologic type a

 Minimally invasive

25 (47)

   

 Encapsulated angioinvasive

15 (28)

   

 Widely invasive

13 (25)

   

Lymph node metastasis

 Present

5 (9)

–

–

–

Distant metastasis

 Present

2 (4)

–

–

–

AJCC stage

 I~II

51 (96)

–

–

–

 III~IV

2 (4)

–

–

–

Follow-up time

 Median (Quartiles)

56 (46–65)

55 (42–65)

55 (47–60)

55 (29–74)

Disease Persistence/Recurrence

 Yes

8 (15)

0 (0)

0 (0)

0 (0)

 No

45 (85)

48 (100)

32 (100)

16 (100)

  1. a, based on the 2017 World Health Organization classification of endocrine tumors; Abbreviations: FTC follicular thyroid carcinoma, FTA follicular thyroid adenoma, FT-UMP follicular tumor of uncertain malignant potential, WDT-UMP well-differentiated tumor of uncertain malignant potential, AJCC American Joint Committee on Cancer, 8th edition staging;