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Table 2 EIF1AX mutations were summarized based on our results, COSMIC database, cBioPortal for cancer genomics database and previous studies (references14–15, 23–27)

From: Mutation profiles of follicular thyroid tumors by targeted sequencing

Disease Cases EIF1AX exon2 mutations EIF1AX intron5/exon6 mutations a
  Total cases With RAS Mut Total cases With RAS Mut
FA/HN 15 10 0 5 2
FT-UMP 1 1 0 0 0
PTC 10 4 0 6 4
FTC 7 0 0 7 4
PDTC 13 3 3 10 8
ATC 14 5 5 9 9
  1. a, A113_splice mutation and G124* mutations
  2. Abbreviations: FA/HN follicular adenoma/hyperplastic nodules, FT-UMP follicular tumor with uncertain malignant potential, PTC papillary thyroid carcinoma, FTC follicular thyroid carcinoma, PDTC poorly differentiated thyroid carcinoma, ATC anaplastic thyroid carcinoma