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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Primary intraosseous hybrid epithelioid schwannoma/perineurioma in the proximal tibia: a case report of benign hybrid neoplasm with local hypercellularity

Fig. 4

Histological and immunohistochemical characteristics of the hypercellular areas. a. The spindle cells arranged in a fascicular or storiform growth pattern. Focally, cells have a streaming or syncytial pattern. Haematoxylin-eosin staining, 400x magnification. b-c. EMA (b) and S100(c) expression was detected. Most spindle cells showed EMA+/S100- staining, only scattered cells exhibited the opposite expression pattern. Immunohistochemical staining, 400x magnification. d. The hypercellular (black arrow) areas and the surrounding hypocellular areas(black asterisk) formed a vague boundary at low magnification. Haematoxylin-eosin staining, 200x magnification. e-f. The boundaries between hypercellular (black arrow) and hypocellular (black asterisk) area were demonstrated by non-overlapping expression of EMA (e) and S100 (f) in the same field as Fig. 4d. Immunohistochemical staining, 200x magnification

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Diagnostic Pathology

ISSN: 1746-1596

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