Clinicopathological characteristics and molecular abnormalities of primary grade 2 neuroendocrine tumors of the cervix

Table 2 The genetic changes of the 3 patients

sample	genename	Achange	Exonicfuction
case1	FCGR3A	missense	p.L66R
case1	STK36	missense	p.R1112Q
case1	TNK2	missense	p.R877H
case1	DAXX	missense	p.A486G
case1	EZR	missense	p.N6S
case1	HIF1A	missense	p.A588T
case1	SEPT9	missense	p.P127L
case1	SLC45A3	nonframeshift deletion	p.222_234del
case1	MAGI1	nonframeshift insertion	p.T422delinsQT
case1	EP400	nonframeshift deletion	p.2728_2728del
case2	PDE4DIP	missense	p.A272T
case2	PAX8	missense	p.P263L
case2	MLH1	missense	p.R217C
case2	SDHA	missense	p.A5333V
case2	MET	missense	p.N375S
case2	TET1	missense	p.S487 L
case2	BRCA2	missense	p.I3412V
case2	ASXL1	missense	p.G652S
case2	MAGI1	nonframeshift insertion	p.T422delinsQT
case3	PMS1	missense	p.R883H
case3	UGT1A3	missense	p.R45W
case3	UGT1A5,UGT1A8,UGT1A10,UGT1A6,UGT1A7,UGT1A3,UGT1A1,UGT1A9,UGT1A4	missense	p.P364L
case3	XPC	missense	p.L48F
case3	ITK	missense	p.L582 M
case3	NOTCH4	missense	p.G534S
case3	IGF2R	missense	p.N2348S
case3	AKAP9	missense	p.R3712Q
case3	EPHB4	missense	p.A371V
case3	RET	missense	p.T278 N
case3	KAT6B	missense	p.V1499I
case3	NUMA1	missense	p.L344 V
case3	ADAMTS20	missense	p.S1273F
case3	ADAMTS20	missense	p.R1000H
case3	YES1	missense	p.I198V
case3	BCR	missense	p.D1106N
case3	SLC45A3	nonframeshift deletion	p.222_234del
case3	BCR	frameshift insertion	p.S1092 fs

ISSN: 1746-1596