High expression of MRE11 correlates with poor prognosis in gastric carcinoma

Diagnostic Pathology

Table 2 Associations of MRE11 expression with clinical parameters in GC

Characteristic	No.	MRE11 Expression		χ²	P
		Low(N = 73)	High(N = 82)	Value	Value
Age		59.84 ± 10.87	56.92 ± 13.24
<60y	78	35	43	0.312	0.576
≥60y	77	38	39	0.312	0.576
Gender
Man	99	48	51	0.212	0.645
Female	56	25	31	0.212	0.645
Tumour location
Proximal	33	14	19	2.575	0.462
Middle	29	17	12
Distal	58	28	30
More than 2	35	14	21
Tumour size
< 5 cm	68	34	34	0.410	0.522
≥5 cm	87	39	48	0.410	0.522
Histologic type
Adenocarcinoma (NOS)	132	63	69	1.868	0.600
Signet ring	9	4	5
Mucinous	12	6	6
Undifferentiated	2	0	2
Bornmann classification
I	8	2	6	2.107	0.550
II	34	18	16
III	97	45	52
IV	16	8	8
Differentiation
Well	3	2	1	1.517	0.468
Moderate	35	19	16
Poor	117	52	65
Depth of invasion
T1	15	10	5	4.146	0.246
T2	13	8	5
T3	84	36	48
T4	43	19	24
Lymph node metastasis
N0	45	26	19	8.269	0.041
N1	54	25	29
N2	23	5	18
N3	33	17	16
Distant metastasis
M0	126	65	61	5.450	0.020
M1	29	8	21	5.450	0.020
Tumour-Node-Metastasis stage
I + II	49	30	19	5.740	0.017
III + IV	106	43	63	5.740	0.017
CEA level (μg/L)
< 5	135	64	71	0.041	0.840
≥5	20	9	11	0.041	0.840

ISSN: 1746-1596