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Fig. 6 | Diagnostic Pathology

Fig. 6

From: LncRNA DNM3OS promotes proliferation and inhibits apoptosis through modulating IGF1 expression by sponging MiR-126 in CHON-001 cells

Fig. 6

DNM3OS down-regulation repressed migration and invasion by acting as a miR-126 sponge. (a) CHON-001 cells migration was inhibited by silencing DNM3OS, which reversed by miR-126 inhibitor using wound healing assay. (b) The distance of scratch was quantified. (c) CHON-001 cells invasion was inhibited by silencing DNM3OS, which was reversed by miR-126 inhibitor using transwell assay. (d) The number of invasion cells was quantified. aP < 0.05 vs. MC, bP < 0.05 vs. M, cP < 0.05 vs. IC, dP < 0.05 vs. I, eP < 0.05 vs. siDNM3OS. M: miR-126 mimic; I: miR-126 inhibitor; MC: miR-126 mimic control; IC: miR-126 inhibitor control; siDNM3OS: small interfering dynamin 3 opposite strand

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