Table 2 List of patients with clinical, immunohistochemical and FISH data
ID | Sex | Age yrs | Histo-logy | Stage | Meta-stases | TFAP2B IHC | ALK IHC | OLIG2 IHC | FISH PAX3/7-FOXO1 fusion |
|---|---|---|---|---|---|---|---|---|---|
1 | F | 2 | ARMS | IV | M1 | + | + | +/− | inconclusive, FOXO1 amp. |
2 | M | 15 | ARMS | IV | M1 | + | + | – | PAX3-FOXO1 |
3 | M | 14 | ARMS | II | M0 | + | + | + | PAX3-FOXO1 |
4 | M | 3.5 | ARMS | II | M0 | + | + | + | PAX3-FOXO1 |
5 | M | 1.5 | ARMS | II | M1 | + | + | + | inconclusive |
6 | M | 8 | ARMS | IV | M1 | + | + | + | PAX7-FOXO1 and amp. |
7 | F | 3 | ARMS | IV | M1 | + | + | + | PAX3-FOXO1 |
8 | M | < 1 | ARMS | IV | M1 | – | – | – | negative |
9 | M | 17 | ARMS | IV | M1 | – | – | – | negative |
10 | F | 10 | ARMS | IV | M1 | +/− | – | – | negative |
11 | F | < 1 | ARMS | II | M1 | – | +/− | – | negative |
12 | M | 4.5 | ERMS | II | M0 | + | + | + | PAX3-FOXO1 |
13 | F | 7.5 | ERMS | III | M0 | + | + | + | PAX3-FOXO1 |
14 | M | 12 | ERMS | III | M1 | + | – | – | PAX3-FOXO1 |
15 | F | 1.5 | ERMS1 | na | na | + | +/− | – | negative |
16 | F | 4 | ERMS | III | M0 | – | + | – | negative |
17 | M | 16 | ERMS | II | M0 | – | – | – | negative |
18 | M | 8 | ERMS | IV | M1 | – | – | – | negative |
19 | M | 14 | ERMS | IV | M1 | – | – | – | negative |
20 | M | 9 | ERMS | III | M0 | – | – | – | negative |
21 | M | 4 | ERMS | I | M0 | – | – | – | negative |
22 | F | 5 | ERMS | III | M1 | – | – | – | negative |
23 | F | < 1 | ERMS | II | na | – | – | – | negative |
24 | M | 7 | ERMS | I | M0 | – | – | – | negative |
25 | M | 7 | ERMS | II | M0 | – | – | – | negative |
26 | F | 5 | ERMS | I | M0 | – | – | – | negative |
27 | M | < 1 | ERMS | I | M0 | +/− | – | – | inconclusive |
28 | F | 1 | ERMS | IV | M1 | +/− | – | – | negative |
29 | M | 2 | ERMS | III | M1 | – | + | – | negative |
30 | M | 17 | ERMS | III | M0 | – | – | – | nd |
31 | M | < 1 | ERMS | III | M0 | – | – | – | nd |
32 | F | 4.5 | ERMS | IV | M1 | – | – | – | nd |
33 | M | < 1 | ERMS | I | M0 | – | – | – | nd |
34 | M | 3 | ERMS | III | M0 | – | – | – | nd |
35 | M | 7 | ERMS | III | M0 | – | – | – | nd |
36 | M | 3 | ERMS | II | M0 | – | – | – | nd |
37 | F | 6 | ERMS | III | M0 | – | – | – | nd |
38 | M | 10 | ERMS | III | na | – | – | – | nd |
39 | M | 11 | ERMS | I | M0 | – | – | – | nd |
40 | M | 1 | ERMS | I | M0 | – | – | – | nd |
41 | M | 11 | ERMS | IV | M1 | – | – | – | nd |
42 | F | 7 | ERMS | IV | M1 | – | – | – | nd |
43 | F | 15 | ERMS | III | M0 | – | – | – | nd |
44 | M | 3 | ERMS | II | M0 | – | – | – | nd |
45 | F | 1 | ERMS | na | na | – | – | – | nd |