Fig. 3

Immunohistochemical Profile of Plasmacytoid Urothelial Carcinoma in the Right Abdominal Wall. Hematoxylin and Eosin demonstrates carcinoma in sheets splaying the skeletal muscle (a). The neoplastic cells are diffusely positive for GATA-3 (b), CK20 (c), and CK7 (d). A subset of neoplastic cells is positive for CD 138 (e). E-cadherin is negative (f). Additional immunohistochemical stains show the tumor cells are diffusely positive for pancytokeratin, patchy expression of CK903, and p53, and focal expression of PAX-8 and negative for CDX-2, p63, NKX3.1, PAX-2 and PSA