Table 4 Heterogeneity of PRMT1, ZEB1, RUNX1 and TWIST1 immunohistochemical expression among different tumor types
Histological subtype | PRMT1 | ZEB1 | RUNX1 | TWIST1 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
+ | +/− | – | + | +/− | – | + | +/− | – | + | −/+ | – | |
ccRCC | 24 (20.0) | 49 (40.8) | 47 (39.2) | 4 (3.5) | 32 (27.8) | 79 (68.7) | 12 (10.2) | 58 (49.6) | 47 (40.2) | 51 (43.6) | 63 (53.8) | 3 (2.6) |
pRCC I | 2 (28.6) | 2 (28.6) | 3 (42.9) | 0 (0.0) | 0 (0.0) | 7 (100) | 0 (0.0) | 2 (28.6) | 5 (71.4) | 4 (57.2) | 3 (42.8) | 0 (0.0) |
pRCC II | 3 (18.8) | 9 (56.2) | 4 (25.0) | 0 (0.0) | 1 (6.3) | 15 (93.8) | 0 (0.0) | 7 (43.7) | 9 (56.3) | 11 (64.6) | 5 (29.4) | 0 (0.0) |
chRCC | 7 (25.0) | 5 (17.9) | 16 (57.1) | 0 (0.0) | 2 (7.4) | 25 (92.6) | 0 (0.0) | 13 (48.2) | 14 (51.8) | 20 (74.1) | 7 (25.9) | 0 (0.0) |
RO | 18 (72.0) | 6 (24.0) | 1 (4.0) | 6 (24.0) | 18 (72.0) | 1 (4.0) | 0 (0.0) | 9 (36.0) | 16 (64.0) | 25 (100) | 0 (0.0) | 0 (0.0) |
CDC | 3 (42.9) | 2 (28.6) | 2 (28.6) | 0 (0.0) | 3 (42.9) | 4 (57.1) | 0 (0.0) | 3 (60.0) | 2 (40.0) | 5 (83.3) | 1 (16.7) | 0 (0.0) |
MLCRN-LMP | 3 (60.0) | 2 (40.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 5 (100) | 1 (20.0) | 3 (60.0) | 1 (20.0) | 3 (60.0) | 2 (40.0) | 0 (0.0) |
P value | p < 0.001* | p < 0.001* | p = 0.183 | p < 0.001* | ||||||||