Table 3 Association between CD68+ cell count, CD20 expression and patients’ cinico-pathological features
From: The role of CD68+ macrophage in classical Hodgkin lymphoma patients from Egypt
Characteristics | CD20 protein n(%) | P valuea | CD68 cell count n(%) | P valueb | |||
|---|---|---|---|---|---|---|---|
Low (n = 30) | Moderate (n = 17) | High (n = 21) | < 20 (42) | ≥20(39) | |||
Age | |||||||
< 40 | 13(43.3) | 10(58.8) | 11(52.4) | 0.64 | 24(57.1) | 15(38.5) | 0.09 |
≥ 40 | 17(56.7) | 7(41.2) | 10(47.6) | 18(42.9) | 24(61.5) | ||
Gender | |||||||
Male | 19(63.3) | 12(70.6) | 12(57.1) | 0.86 | 28(66.7) | 23(59.0) | 0.47 |
Female | 11(36.7) | 5(29.4) | 9(42.9) | 14(33.3) | 16(41.0) | ||
Stage | |||||||
I-II | 7(23.3) | 8(47.1) | 11(52.4) | 0.048* | 17(40.5) | 11(28.2) | 0.25 |
III-IV | 23(76.7) | 9(52.9) | 10(47.6) | 25(59.5) | 28(71.8) | ||
B-symptoms | |||||||
Negative | 21(70.0) | 14(82.4) | 14(66.7) | 0.70 | 31(73.8) | 28(71.8) | 0.84 |
Positive | 9(30.0) | 3(17.6) | 7(33.3) | 11(26.2) | 11(28.2) | ||
Bulky disease | |||||||
Negative | 25(83.3) | 15(88.2) | 15(71.4) | 0.56 | 33(78.6) | 33(84.6) | 0.48 |
Positive | 5(6.7) | 2(11.8) | 6(28.6) | 9(21.4) | 6(15.4) | ||
IPS | |||||||
Low risk< 4 | 20(66.7) | 16(94.1) | 16(76.2) | 0.21 | 33(78.6) | 29(74.4) | 0.66 |
High risk ≥4 | 10(33.3) | 1(5.9) | 5(23.8) | 9(21.4) | 10(25.6) | ||
Pathology | |||||||
Mixed cellularity | 11(36.7) | 8(47.1) | 9(42.9) | 0.55 | 15(35.7) | 18(46.2) | 0.63 |
Nodular necrosis | 17(56.7) | 8(47.1) | 12(57.1) | 25(59.5) | 20(51.3) | ||
Lymphocyte-rich | 2(6.7) | 0(0.0) | 0(0.0) | 1(2.4) | 1(2.6) | ||
Lymphocyte-depleted | 0(0.0) | 1(5.9) | (0.0) | 1(2.4) | 0(0.0) | ||