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Table 2 Comparison of pathologic parameters

From: Comparative pathologic analysis of mediastinal B-cell lymphomas: selective expression of p63 but no GATA3 optimally differentiates primary mediastinal large B-cell lymphoma from classic Hodgkin lymphoma

  CHL, NS (N = 13)PMLBCL (N = 16)p valueGray
(N = 3)
GranulomaPresent or absent3(23.1%):10(76.9%)0:16(100%)0.0780:3
FibrosisDiffuse/nodular/reticular/none8(61.5%):5(38.5%):0:01(6.2%):1(6.2%):12(75.0%):2(12.5%)< 0.0011:2
CD20Negative/focal/diffuse11(84.6%):2(13.4%):00:6(37.5%):10(62.5%)< 0.0010:3:0
CD23Positive (> 30%) or negative1(8.3%):11(91.7%)a6(37.5%):10(62.5%)0.0242:1
CD30Diffuse/ focal/negative13(100%):0:06(37.5%):6(37.5%):4(25.0%)0.0012:1
IRF4/MUM1Positive (> 30%) or negative13(100%):0(0%)8(50.0%):8(50.0%)0.0032:1
BCL6Positive (> 30%) or negative0:12(100%)a9(56.2%):7(43.8%)0.0031:2
CD10Positive (> 30%) or negative0:12(100%)a1(6.3%):15(93.7%)1.0000:3
COOGC or non-GCB0:12(100%)a6(37.5%):10(62.5%)0.0240:3
EBVPresent or absent1(7.7%):12(92.3%)1(6.2%):15(93.8%)1.0000:3
P63Positive (> 5%) or negative2(15.4%):11(84.6%)15(93.8%):1(6.2%)< 0.0012:1
GATA3Positive (> 5%) or negative10(76.9%):3(23.1%)0:16(100%)< 0.0012:1
CyclinEPositive (> 5%) or negative0:13(100%)2(12.5%):14(87.5%)0.4920:3
  1. CHL classic Hodgkin lymphoma, NS nodular sclerosis, PMLBCL primary mediastinal diffuse large B-cell lymphoma (DLBCL); Gray, B-cell lymphoma unclassifiable, with features intermediate between DLBCL and classic Hodgkin lymphoma
  2. a: immunohistochemistry for some antibodies was not done in one case due to exhaustion of stored tissues