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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Primary non-Hodgkin lymphoma of the tongue base: the clinicopathology of seven cases and evaluation of HPV and EBV status

Fig. 2

The case of DLBCL showing HPV DNA positivity (case 6). a. H&E showed a diffuse infiltrate of large cells with an obvious nucleolus and abundant cytoplasm (200 x). b. Tumour cells diffusely expressed CD20 (200 x). c. Immunohistochemistry staining showed diffuse and strong staining of P16 protein (40 x) d. Immunohistochemistry staining showed diffuse and strong staining of P16 protein (100 x). e. HPV DNA ISH showed brown punctate dots in the tumour cell nucleus or cytoplasm (400x).f. HPV RNA ISH all negative

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Diagnostic Pathology

ISSN: 1746-1596

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