Skip to main content

Table 3 Sensitivity and specificity of each criterion of Gerami and Gaiser in differentiating dysplastic nevi and early-stage acral and cutaneous melanomas

From: Four-color fluorescence in-situ hybridization is useful to assist to distinguish early stage acral and cutaneous melanomas from dysplastic junctional or compound nevus

 SensitivitySpecificity
Gerami’s criteria
 RREB1 > CEP6 (> 55%)15.2%100%
 RREB1 > 2 (> 29%)74.6%94.0%
 MYB<CEP6 (> 40%)40.7%98.0%
 CCND1 > 2 (> 38%)91.5%94.0%
 Totala94.9%94.0%
Gaiser’s criteria
 RREB1 aberrant (> 63%)47.5%94.0%
 MYB<CEP6 (> 31%)50.8%98.0%
 MYB ≥ 2.547.5%94.0%
 CCND1 ≥ 2.588.1%94.0%
 Totala93.2%90.0%
  1. a total sensitivity and specificity of the four criteria, fulfilling any of the four criteria is considered positive