Table 3 Comparison of clinicopathological features between multiple sporadic GISTs and primary GISTs with only one lesion
Multiple sporadic GISTs (58 tumors from 27 patients) | Primary GIST with one lesion (1066 tumors from 1066 patients) | p | ||
|---|---|---|---|---|
Age (years) | ≤60 | 14.8%, 4/27 | 48.8%, 520/1066 | < 0.001 |
> 60 | 85.2%, 23/27 | 51.2%, 546/1066 | ||
Sex | Male | 33.3%, 9/27 | 53.7%, 572/1066 | 0.037 |
Female | 66.7%, 18/27 | 46.3%, 494/1066 | ||
location | Stomach | 84.5%, 49/58 | 60.3%, 643/1066 | < 0.001 |
Non-stomach | 15.5%, 9/58 | 39.7%, 423/1066 | ||
Tumor size | ≤2 cm | 60.3%, 35/58 | 10.7%, 114/1066 | < 0.001 |
2-5 cm | 22.4%, 13/58 | 42.8%, 456/1066 | ||
5-10 cm | 15.5%, 9/58 | 34.1%, 363/1066 | ||
> 10 cm | 1.7%, 1/58 | 12.5%, 133/1066 | ||
Mitosis | ≤5/50HPF | 94.8%, 55/58 | 75.7%, 807/1066 | 0.002 |
6–10/50HPF | 3.4%, 2/58 | 12.9%, 137/1066 | ||
> 10/50HPF | 1.7%, 1/58 | 11.4%, 122/1066 | ||
Risk assessment (modified NIH) | VLR | 60.3%, 35/58 | 9.4%, 100/1066 | < 0.001 |
LR | 20.7%, 12/58 | 38.2%, 407/1066 | ||
IR | 10.3%, 6/58 | 17.5%, 187/1066 | ||
HR | 8.6%, 5/58 | 34.9%, 372/1066 | ||