Table 2 Univariate and multivariate analyses of prognostic variables for overall survival in GA patients using Cox proportional hazards regression
From: Gli1 regulates stemness characteristics in gastric adenocarcinoma
Characteristic | Univariate analyses | Multivariate analyses | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age (years) | Â | Â | 0.202 | Â | Â | 0.494 |
 < 65 | 1.00 |  | – | 1.00 |  | – |
 ≥ 65 | 1.326 | 0.859–2.044 |  | 1.178 | 0.737–1.882 |  |
Tumor size (cm) | Â | Â | 0.007* | Â | Â | 0.888 |
 < 4.5 | 1.00 |  |  | 1.00 |  |  |
 ≥ 4.5 | 1.918 | 1.190–3.091 |  | 1.042 | 0.591–1.835 |  |
pT stage |  |  | < 0.001* |  |  | < 0.001* |
 1 | 1.00 |  |  | 1.00 |  |  |
 2 | 4.944 | 1.440–16.974 |  | 1.639 | 1.154–22.990 |  |
 3 | 12.358 | 3.875–39.412 |  | 2.352 | 2.472–44.689 |  |
 4 | 20.989 | 4.690–93.938 |  | 3.854 | 7.152–311.452 |  |
Lymph node metastasis |  |  | < 0.001* |  |  | < 0.001* |
 Negative | 1.00 |  | – | 1.00 |  | – |
 Positive | 5.610 | 3.446–9.133 |  | 3.272 | 1.908–5.613 |  |
Distant metastasis |  |  | < 0.001* |  |  | 0.002* |
 Negative | 1.00 |  | – | 1.00 |  | – |
 Positive | 5.050 | 2.952–8.640 |  | 2.528 | 1.416–4.513 |  |
Gli1 |  |  | < 0.001* |  |  | 0.002* |
 Negative | 1.00 |  | – | 1.00 |  | – |
 Positive | 5.245 | 2.401–11.458 |  | 3.572 | 1.573–8.112 |  |