Fig. 5

Depletion of miR-152 weakened the impacts of circKIF4A knockdown on migration, invasion and apoptosis of BC cells. MCF-7 and MDA-MB-231 cells were assigned to si-circKIF4A, si-NC, si-circKIF4A + anti-miR-152 and si-circKIF4A + anti-miR-NC groups. (a) The expression of miR-152 was detected by qRT-PCR. (b and c) Cell migration and invasion were evaluated by transwell assay. (d) Cell apoptosis ability was evaluated using flow cytometry assay. (e) Caspase-3 level was examined by qRT-PCR. **P < 0.01, ***P < 0.001