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Fig. 1 | Diagnostic Pathology

Fig. 1

From: A familial case of alveolar capillary dysplasia with misalignment of the pulmonary veins: the clinicopathological features and unusual glomeruloid endothelial proliferation

Fig. 1

Histologic and immunohistochemical features of the third child. a A macroscopic image (left) and the cut surface (right) of the right lung before formalin fixation. Congestion and loss of elasticity were noted. b A misaligned pulmonary vein (v) is adjacent to a pulmonary artery within the same adventitial sheath (a). A bronchiole (b) abuts the vein and artery. c Thickening of the alveolar wall. Immunohistochemical staining for CD34 highlights the dilation of the capillary of the alveolar septa (inset). In this case, a decrease in the number of alveolar capillaries is not remarkable. d-f) Low-power (d, e) and high-power (f) views of the interlobular septum. Vessels with glomeruloid endothelial proliferation (arrow) contrast with blood vessels (arrowhead). The vessels are dilated and contain no or few red blood cells

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