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Fig. 6 | Diagnostic Pathology

Fig. 6

From: Prognostic perspectives of PD-L1 combined with tumor-infiltrating lymphocytes, Epstein-Barr virus, and microsatellite instability in gastric carcinomas

Fig. 6

Effect of PD-L1 knockdown on cell biologic properties in EBV-negative gastric carcinoma cell lines. SNU 601 cells (in left column) show lower cell proliferation (a), invasion (b) and migration (c), and higher apoptosis (d) in PD-L1-specific siRNA cells than scrambled siRNA-transfected mock cells (P < 0.05). However, in SNU216 cells (in middle column) and AGS cells (in right column), PD-L1-specific siRNA cells reveal statistically significant decreases in invasion and migration compared to scrambled siRNA-transfected mock cells (P < 0.05), but not statistically significant changes in proliferation and apoptosis

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Diagnostic Pathology

ISSN: 1746-1596

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