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Table 3 Association among histopathological findings of liver biopsy in BA patients after Kasai procedure

From: Histopathological findings for prediction of liver cirrhosis and survival in biliary atresia patients after Kasai procedure

Histopathological findings Bile duct proliferation p-value OR (95% CI)
Severe Moderate/mild
Cholestasis
√ Severe 18 1 7.3 × 10−5* 28.5 (3.4–242.1)
√ Moderate/mild/absent 12 19   
Portal inflammation
√ Severe 17 1 2 × 10−4* 24.8 (2.9–210.5)
√ Moderate/mild 13 19   
Giant cell transformation
√ Positive 15 13 0.39 0.5 (0.2–1.7)
√ Negative 15 7   
  Cholestasis   
  Severe Moderate/mild/absent   
Portal inflammation
√ Severe 11 7 0.016* 4.7 (1.4–16.3)
√ Moderate/mild 8 24   
Giant cell transformation
√ Positive 8 20 0.15 0.4 (0.1-
√ Negative 11 11   1.3)
  Portal inflammation   
  Severe Moderate/mild   
Giant cell transformation
√ Positive 11 17 0.77 1.4 (0.4–4.5)
√ Negative 7 15   
  1. BA biliary atresia, OR odds ratio, CI confidence interval
  2. *, p < 0.05 is considered statistically significant