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Table 1 Indication for and added clinical value of clinician-initiated blood smear reviews

From: Clinician-ordered peripheral blood smears have low reimbursement and variable clinical value: a three-institution study, with suggestions for operational efficiency

Indication

Smears for this indication, among all smears performed (%)

Smears with added clinical value, among smears performed for this indication (%)

Any

515 (100%)

118 (23%)

Any RBC abnormality

259 (50%)

48 (19%)a

Any WBC cell abnormality

126 (24%)

32 (25%)a

Any PLT abnormality

150 (29%)

20 (13%)a

Any cytosis

53 (10%)

18 (34%)

 Erythrocytosis

2 (0%)

0 (0%)

 Leukocytosis

42 (8%)

18 (43%)

 Thrombocytosis

12 (2%)

1 (8%)

Any cytopenia

267 (52%)

45 (17%)

 Anemia

179 (35%)

32 (18%)

 Leukopenia

79 (15%)

11 (14%)

 Thrombocytopenia

135 (26%)

18 (13%)

Any abnormal cell morphology

39 (8%)

9 (23%)

 RBC morphology

22 (4%)

4 (18%)

 WBC morphology

6 (1%)

3 (50%)

 PLT morphology

5 (1%)

1 (20%)

Hematolymphoid neoplasm

65 (13%)

30 (46%)

Blasts

5 (1%)

2 (40%)

Hemolysis

100 (19%)

24 (24%)

Parasites

4 (1%)

1 (25%)

Other

55 (11%)

15 (27%)

Not specified

33 (6%)

6 (18%)

  1. aThe proportion of smears with potential clinical value differed significantly across these three categories of indications (p = 0.0375)
  2. RBC Red blood cell, WBC White blood cell, PLT Platelet