Table 3 Immunohistochemical profile of SPN cases in patients under 20 years of age (n = 29)
S. No | Immunohistochemical Antibody | No of cases in which performed | Positive | Type of staining | Negative |
|---|---|---|---|---|---|
1 | TFE3 | 21 | 12(57.2%) | Nuclear | 9(42.8%) |
2 | Cyclin D1 | 13 | 12(92.3%) | Nuclear | 1(7.7%) |
3 | Beta Catenin | 16 | 15(93.8%) | Nuclear | 1(6.2%) |
4 | CD99 (mic2) | 6 | 6(100%) | Cytoplasmic dot-like | – |
5 | CD10 | 25 | 25(100%) | Cytoplasmic | – |
6 | CD56 | 19 | 19(100%) | Membranous | – |
7 | Progesterone Receptor (PR) | 13 | 13(100%) | Nuclear | – |
8 | Vimentin | 8 | 8(100%) | Cytoplasmic | – |
9 | Cytokeratin AE1/AE3 | 26 | 19(73.1%) | Cytoplasmic | 7(26.9%) |
10 | Chromogranin A | 10 | 2(20%) | Cytoplasmic | 8(80%) |
11 | Synaptophysin | 22 | 13(59.1%) | Cytoplasmic | 9(40.9%) |