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Table 3 Immunohistochemical profile of SPN cases in patients under 20 years of age (n = 29)

From: Clinicopathological and immunohistochemical study of 29 cases of solid-pseudopapillary neoplasms of the pancreas in patients under 20 years of age along with detailed review of literature

S. No Immunohistochemical Antibody No of cases in which performed Positive Type of staining Negative
1 TFE3 21 12(57.2%) Nuclear 9(42.8%)
2 Cyclin D1 13 12(92.3%) Nuclear 1(7.7%)
3 Beta Catenin 16 15(93.8%) Nuclear 1(6.2%)
4 CD99 (mic2) 6 6(100%) Cytoplasmic dot-like
5 CD10 25 25(100%) Cytoplasmic
6 CD56 19 19(100%) Membranous
7 Progesterone Receptor (PR) 13 13(100%) Nuclear
8 Vimentin 8 8(100%) Cytoplasmic
9 Cytokeratin AE1/AE3 26 19(73.1%) Cytoplasmic 7(26.9%)
10 Chromogranin A 10 2(20%) Cytoplasmic 8(80%)
11 Synaptophysin 22 13(59.1%) Cytoplasmic 9(40.9%)