Table 2 Pathological examination of the placental samples of the pregnant women with COVID-19 pneumonia
From: Placental pathology of the third trimester pregnant women from COVID-19
| Pathological diagnosis | patient | |||||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
| Category I: Maternal vascular malperfusion | ||||||||
| Central placental infarct(s) | √ | |||||||
| Peripheral placental infarct | √ | |||||||
| Distal villous hypoplasia | √ | |||||||
| Accelerated villous maturation pattern | ||||||||
| Increased syncytial knots | √ | √ | √ | √ | √ | √ | √ | √ |
| Villous agglutination | ||||||||
| Category II:maternal decidual arteriopathy | ||||||||
| Insufficient vessel remodelling | ||||||||
| Fibrinoid necrosis | ||||||||
| Category III:Fetal vascular malperfusion (FVM) | ||||||||
| Avascular fibrotic villi | ||||||||
| Thrombosis | ||||||||
| Intramural fibrin deposition | ||||||||
| Villous stromal-vascular karyorrhexis | ||||||||
| Stem villous vascular obliteration | ||||||||
| High-grade fetal vascular malperfusion | ||||||||
| Category IV:Ascending intrauterine infection | ||||||||
| Maternal inflammatory response (mild) | √ | √ | ||||||
| Fetal inflammatory response | ||||||||
| Category V:Fibrinoid | ||||||||
| Increased focal perivillous fibrin depositions (perivillous fibrin plaque) | √ | √ | √ | √ | √ | √ | √ | |
| Massive perivillous fibrin deposition pattern | √ | |||||||
| Maternal floor infarct pattern | ||||||||
| Category VI:Chronic inflammation | ||||||||
| Chronic intervillositis | ||||||||
| Chronic plasma cell deciduitis | √ | √ | ||||||
| Chronic chorioamnionitis | ||||||||
| Category VII:Other placental findngs | ||||||||
| Microscopic accreta | ||||||||
| Villous edema | √ | |||||||
| Membranes with hemorrhage | ||||||||
| Acute intervillositis (mild) | √ | |||||||