Placental pathology of the third trimester pregnant women from COVID-19

Diagnostic Pathology

Table 2 Pathological examination of the placental samples of the pregnant women with COVID-19 pneumonia

Pathological diagnosis	patient
Pathological diagnosis	1	2	3	4	5	6	7	8
Category I: Maternal vascular malperfusion
Central placental infarct(s)		√
Peripheral placental infarct			√
Distal villous hypoplasia								√
Accelerated villous maturation pattern
Increased syncytial knots	√	√	√	√	√	√	√	√
Villous agglutination
Category II:maternal decidual arteriopathy
Insufficient vessel remodelling
Fibrinoid necrosis
Category III:Fetal vascular malperfusion (FVM)
Avascular fibrotic villi
Thrombosis
Intramural fibrin deposition
Villous stromal-vascular karyorrhexis
Stem villous vascular obliteration
High-grade fetal vascular malperfusion
Category IV:Ascending intrauterine infection
Maternal inflammatory response (mild)				√	√
Fetal inflammatory response
Category V:Fibrinoid
Increased focal perivillous fibrin depositions (perivillous fibrin plaque)		√	√	√	√	√	√	√
Massive perivillous fibrin deposition pattern		√
Maternal floor infarct pattern
Category VI:Chronic inflammation
Chronic intervillositis
Chronic plasma cell deciduitis						√		√
Chronic chorioamnionitis
Category VII:Other placental findngs
Microscopic accreta
Villous edema								√
Membranes with hemorrhage
Acute intervillositis (mild)								√

ISSN: 1746-1596