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Table 1 Clinicopathological characteristics of the 60 patients with CINs

From: Accuracy of HPV E6/E7 mRNA examination using in situ hybridization in diagnosing cervical intraepithelial lesions

Parameters Numbers Percent
Age at diagnosis, (Mean;range) 33.0 ± 8.8 18–65
Smoking history
Yes 5 8.3%
No 55 91.7%
Drinking
Yes 10 16.7%
No 50 83.3%
Education
Primary 1 1.7%
Secondary 20 38.3%
College and above 36 60.0%
Fertility status
Nulliparous 26 43.3%
Pluriparous 34 56.7%
Menopausal status
Pre-menopausal 57 95%
Post-menopausal 3 5%
BMI
Normal(18.5-25) 46 76.7%
Overweight(> 25) 6 10.0%
Underweight(< 18.5) 8 13.3%
Monthly income
≤10000 34 56.7%
>10000 26 43.3%
Presentation
Contact bleeding 3 5%
Symptomless 57 95%
Screening history
Ever 27 45%
Never 33 55%
Age at first intercourse (Mean;range) 22.0 ± 2.6 18-31
Sex partners
One 42 70.0%
More than one 18 30.0%
Referral Cytology
NILM 26 43.3%
ASC-US 12 20.0%
ASC-H 5 8.3%
LISL 9 15.0%
HISL 8 13.3%
HR-HPV infection
Yes 60 100%
No 0  
CINs detected by
Biopsy 16 26.7%
LEEP/CKC 44 73.3%
Pathological diagnosis
CIN1 27 45.0%
CIN2 17 28.3%
CIN3 16 26.7%
E6/E7mRNA
Positive 35 58.3%
Negative 25 42.7%
p16
Positive 36 60%
Negative 24 40%
Ki67
Positive 42 70%
Negative 18 30%
  1. Monthly income was the average monthly income of an individual family
  2. NILM Negative for intraepithelial lesion or malignancy, ASCUS Atypical squamous cells of undetermined significance, ASC-H Atypical cells cannot exclude high grade, BMI Body mass index