Table 1 Clinicopathological characteristics of the 60 patients with CINs
Parameters | Numbers | Percent |
|---|---|---|
Age at diagnosis, (Mean;range) | 33.0 ± 8.8 | 18–65 |
Smoking history | ||
 Yes | 5 | 8.3% |
 No | 55 | 91.7% |
Drinking | ||
 Yes | 10 | 16.7% |
 No | 50 | 83.3% |
Education | ||
 Primary | 1 | 1.7% |
 Secondary | 20 | 38.3% |
 College and above | 36 | 60.0% |
Fertility status | ||
 Nulliparous | 26 | 43.3% |
 Pluriparous | 34 | 56.7% |
Menopausal status | ||
 Pre-menopausal | 57 | 95% |
 Post-menopausal | 3 | 5% |
BMI | ||
 Normal(18.5-25) | 46 | 76.7% |
 Overweight(> 25) | 6 | 10.0% |
 Underweight(< 18.5) | 8 | 13.3% |
Monthly income | ||
 ≤10000 | 34 | 56.7% |
 >10000 | 26 | 43.3% |
Presentation | ||
 Contact bleeding | 3 | 5% |
 Symptomless | 57 | 95% |
Screening history | ||
 Ever | 27 | 45% |
 Never | 33 | 55% |
Age at first intercourse (Mean;range) | 22.0 ± 2.6 | 18-31 |
Sex partners | ||
 One | 42 | 70.0% |
 More than one | 18 | 30.0% |
Referral Cytology | ||
 NILM | 26 | 43.3% |
 ASC-US | 12 | 20.0% |
 ASC-H | 5 | 8.3% |
 LISL | 9 | 15.0% |
 HISL | 8 | 13.3% |
HR-HPV infection | ||
 Yes | 60 | 100% |
 No | 0 |  |
CINs detected by | ||
 Biopsy | 16 | 26.7% |
 LEEP/CKC | 44 | 73.3% |
Pathological diagnosis | ||
 CIN1 | 27 | 45.0% |
 CIN2 | 17 | 28.3% |
 CIN3 | 16 | 26.7% |
E6/E7mRNA | ||
 Positive | 35 | 58.3% |
 Negative | 25 | 42.7% |
p16 | ||
 Positive | 36 | 60% |
 Negative | 24 | 40% |
Ki67 | ||
 Positive | 42 | 70% |
 Negative | 18 | 30% |