Table 1 Cases of metastases in cirrhotic livers
From: Metastases can occur in cirrhotic livers with patent portal veins
Case | Age (years) | Sex | Resection or biopsy | Original site of tumor | Cause of cirrhosis | Laennec stage (4A, 4B, 4 C) | AST | ALT | Albumin (g/dL) | Platelets (10^3/µL) | Cirrhosis-related sequalae | Echocardiogram (evidence of shunts or septal defects) | Ultrasound doppler information | CD34 aberrant positivity of background cirrhotic liver |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 68 | M | Biopsy | Pancreatic ductal adenocarcinoma | HCV | 4B | 161 | 107 | 3.2 | 292 | None | N/A | Patent main portal vein with no flow reversal | No |
2 | 47 | F | Biopsy | Well-differentiated neuroendocrine tumor (small bowel) | EtOH | 4A/B | 22 | 25 | 4.1 | 195 | None | No evidence of shunt | Patent main portal vein with no flow reversal | No |
3 | 69 | F | Biopsy | Metastatic undifferentiated carcinoma (history of breast carcinoma) | Steatohepatitis | 4 C | 721 | 1166 | 2.8 | 230 | None | No evidence of shunt | Patent main portal vein with no flow reversal | No |
4 | 65 | F | Biopsy | Breast ductal carcinoma | Cryptogenic | 4 C | 134 | 83 | 2.8 | 220 | Ascites; jaundice | N/A | Flow reversal in main portal vein | No |
5 | 66 | M | Biopsy | Lung adenocarcinoma (favored) | EtOH | 4 C | 33 | 26 | 3.6 | 94 | Varices | No evidence of shunt | Flow reversal in portal vein and branches | No |
6 | 77 | F | Biopsy | Poorly differentiated carcinoma with intestinal differentiation (possibly colonic) | Cryptogenic | 4B | 92 | 32 | 2.5 | 150 | Ascites | No evidence of shunt | N/A | No |
7 | 56 | F | Resection | Colorectal adenocarcinoma | HCV | 4A/B | 60 | 33 | 4.4 | 332 | Ascites; collateral vessels | No evidence of shunt | N/A | No |
8 | 67 | F | Resection | Colorectal adenocarcinoma | NASH | 4A | 68 | 35 | 2.6 | 200 | None | No evidence of shunt | N/A | No |
9 | 68 | F | Biopsy | Small cell carcinoma | History of HCV (status post transplant) | 4A | 312 | 155 | 2.2 | 86 | Ascites; portal hypertension; splenomegaly | No evidence of shunt | N/A | No |
10 | 67 | M | Biopsy | Pancreatic ductal adenocarcinoma | HCV | 4 C | 104 | 106 | 4 | 137 | Ascites; varices; portal hypertension | N/A | N/A | N/A |
11 | 59 | M | Biopsy | Well-differentiated neuroendocrine tumor (pancreas) | NASH | 4A | 27 | 27 | 4 | 251 | Ascites | No evidence of shunt | N/A | N/A |
12 | 74 | F | Biopsy | Colorectal adenocarcinoma | NASH | 4 C | 14 | 10 | 4 | 74 | Ascites; splenomegaly; portal hypertension | No evidence of shunt | Patent main portal vein with no flow reversal | N/A |
13 | 78 | M | Biopsy | Colorectal adenocarcinoma | EtOH | 4A | 721 | 109 | 2 | 82 | Ascites; varices; portal hypertension; encephalopathy | N/A | Patent main portal vein with no flow reversal | N/A |
14 | 59 | M | Resection | Well-differentiated neuroendocrine tumor (unknown primary) | EtOH | 4B | N/A | N/A | 3.9 | 11 | Ascites; encephalopathy | N/A | Patent main portal vein with near (but not complete) flow reversal | No |
15 | 48 | M | Resection | Colorectal adenocarcinoma | Cryptogenic | 4A | 47 | 70 | 4.6 | 150 | None | N/A | Patent main portal vein with no flow reversal | No |
16 | 51 | F | Resection | Pancreatic ductal adenocarcinoma | NASH | 4A | 88 | 60 | 4.3 | 259 | None | N/A | N/A | No |
17 | 50 | F | Biopsy | Fallopian tube serous carcinoma | NASH | 4A | 131 | 127 | 3.1 | 341 | None | No evidence of shunt | Patent main portal vein with no flow reversal | N/A |
18 | 65 | M | Biopsy | Colorectal adenocarcinoma | HCV | 4B | 36 | 44 | N/A | 77 | None | N/A | N/A | N/A |
19 | 60 | F | Biopsy | Gastric adenocarcinoma | Steatohepatitis | 4 C | 81 | 40 | 2.3 | 220 | Ascites | No evidence of shunt | Main portal vein with possible nonocclusive thrombus; no flow reversal | N/A |
20 | 73 | F | Wedge biopsy | Duodenal adenocarcinoma | HCV | 4A | 32 | 22 | 3.4 | 119 | None | No evidence of shunt | N/A | N/A |
21 | 62 | F | Biopsy | Pancreatic ductal adenocarcinoma | Cryptogenic | 4A | 45 | 26 | 2.7 | 146 | Ascities | N/A | N/A | N/A |
22 | 75 | F | Biopsy | Metastatic carcinoma of unknown primary | Steatohepatitis | 4 C | 54 | 25 | 2.1 | 127 | Ascites; varices | N/A | N/A | N/A |
23 | 74 | M | Biopsy | Colorectal adenocarcinoma | Steatohepatitis | 4B | N/A | N/A | N/A | N/A | Unknown | N/A | N/A | No |
24 | 57 | F | Biopsy | Pancreatic ductal adenocarcinoma | HCV | 4A | 34 | 14 | 2.4 | 269 | None | No evidence of shunt | N/A | No |