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Fig. 1 | Diagnostic Pathology

Fig. 1

From: CpG islands in MyD88 and ASC/PYCARD/TMS1 promoter regions are differentially methylated in head and neck squamous cell carcinoma and primary lung squamous cell carcinoma

Fig. 1

Position of the tested CpG sites in the ASC/TMS1/PYCARD (a) and MyD88 (b) gene promoters (vertical lines). Methylation status of selected CpC sites in the promoter region of the tested genes (c and d); each bar represents mean percentage methylation (%) of individually tested CpG site; methylation status of all tested CpGs in all tested samples are represented as an average value (%) of at least 3 individual PCR/pyrosequencing reactions. ROC curve analysis for ASC/TMS1/PYCARD CpG8 (e) and MyD88 CpG4 (f) for differentiation of primary HNSCC from primary LuSCC

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