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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review

Fig. 2

Hematoxylin and eosin staining show the tumor exhibited a sheet-like structure with necrosis (a), vesicular nuclei and prominent nucleoli (b) and areas with rhabdoid morphology (c). The tumor cells show a high mitotic rate (d). Tumor cells are positive for (e) CK and (f) vimentin. SMARCA4 (BRG1) (g) was lost, while SMARCA2 (INI-1) (h) was retained in the tumor cell nuclei

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Diagnostic Pathology

ISSN: 1746-1596

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