Table 2 Association between histological subtypes of endometrial carcinoma and either/or co-expression of mesothelin and CA125
From: Significance of mesothelin and CA125 expression in endometrial carcinoma: a retrospective analysis
Histological type | Mesothelin expression | CA125 expression | Co-expression of mesothelin and CA125 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Positive | Negative | p-value | Positive | Negative | p-value | Positive | Negative | p-value | |||||||
(n = 171) | (n = 314) | (n = 368) | (n = 117) | (n = 167) | (n = 318) | ||||||||||
Grade 1 endometrioid carcinoma | 65 | (38%) | 155 | (49%) | 0.027 | 182 | (49%) | 38 | (32%) | < 0.01 | 64 | (38%) | 156 | (49%) | 0.048 |
Grade 2 endometrioid carcinoma | 45 | (26%) | 63 | (20%) | Â | 80 | (22%) | 28 | (24%) | Â | 43 | (26%) | 65 | (21%) | Â |
Grade 3 endometrioid carcinoma | 20 | (12%) | 45 | (15%) | Â | 37 | (10%) | 28 | (24%) | Â | 20 | (12%) | 45 | (14%) | Â |
Other carcinomas | 41 | (24%) | 51 | (16%) | Â | 69 | (19%) | 23 | (20%) | Â | 40 | (24%) | 52 | (16%) | Â |